As we gradually gained success with early diagnosis of skin cancer it became clear that genetics play a role at its development. Multiple skin cancers within a single patient, clusters of skin cancers within families and an increased risk of other cancers types are some examples.
I’ll present important hereditary skin cancer syndromes, review its characteristics and offer an optimal personal and familial surveillance program.
Moving on, we’ll identify pivotal genes which directly contribute to skin cancer development- melanoma and non-melanoma (NMSC) and relate it to drugs available today in the treatment field.
Finally, in a world where personalized medicine is a popular phrase and next generation sequencing (NGS) techniques are becoming accessible I’ll discuss some other candidate genes with a potential effect on response to treatment and adverse effects.